Oxford Centre for Neuroinflammation

Senior Postdoctoral Scientist

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RDM Investigative Medicine, MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford

Grade 8: £41,526 - £49,553 p.a.

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You are invited to apply to join Professor Lars Fugger and his team at the MRC Human Immunology Unit, based at the John Radcliffe Hospital, Oxford. You will join a team of research scientists and statisticians, have access to state-of-the-art technologies and analytical tools as well as collaborate with leading researchers both locally and globally.

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Multiple sclerosis (MS) is an autoimmune disease that attacks the central nervous system, with a core inflammatory component. Disease onset is typically observed in young adults and is characterised by accumulative physical and cognitive disability, with further reduction in quality of life often caused by chronic pain and fatigue. The disease is caused by both genetic and environmental factors, but the exact mechanisms for how their interplay results in disease is unknown. The successful candidate will join part of a research initiative that will use single cell technologies, MS patient samples and genotype-specific recruitment of healthy volunteer blood samples from the Oxford Biobank, with the aim to explain disease cause and heterogeneity.

You must be highly motivated and have the ability to develop new ideas and research objectives in which to advance our understanding of MS. A strong background in human immunology is essential, with experience with primary cell handling and culture. Experience in functional genomes is desirable, in particular in association with large datasets, such as those from genome-wide association studies (GWAS). We continuously endeavour to incorporate new technologies into our research portfolio, so you will be encouraged to demonstrate your experience of technologies that are already used in the group, as well as any additional technologies you feel would be supportive of our research strategy.

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If you would like to discuss this position informally before applying, please email Professor Fugger (lars.fugger@imm.ox.ac.uk).

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Whilst this role is a Grade 8 position, we would be willing to consider candidates with potential but less experience who are seeking a development opportunity, for which the appointment would be at Grade 7 (£32,817 - £40,322 p.a.) with the responsibilities adjusted accordingly. This would be discussed with applicants at interview/appointment, where appropriate.

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Further information regarding the research group of Professors Lars Fugger can be found at: www.imm.ox.ac.uk/wimm-research/mrc-human-immunology-unit/lars-fugger; www.msoxford.co.uk; www.ndcn.ox.ac.uk/team/prinicipal-investigators/lars-fugger

The post is full-time, fixed-term until 31 March 2022, and is available immediately.

Only applications received by 12.00 noon on Wednesday 6 November 2019 will be considered. Interviews will be held as soon as possible thereafter.

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